CJC-1295 (No DAC) + Ipamorelin

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Description

This research blend combines two growth hormone secretagogues with complementary mechanisms: CJC-1295 without DAC (Mod GRF 1-29), a synthetic growth hormone-releasing hormone (GHRH) analog (C152H252N44O42, ~3367.9 g/mol), and Ipamorelin, a selective growth hormone-releasing peptide and ghrelin/GHS-R1a receptor agonist pentapeptide (C38H49N9O5, ~711.9 g/mol). In laboratory and preclinical models, the two peptides are co-administered to investigate synergistic and pulsatile stimulation of somatotroph growth hormone release, acting on distinct receptor pathways to amplify secretory output. This combination is frequently studied for its effects on the growth hormone/IGF-1 signaling axis and Ipamorelin's reported selectivity relative to cortisol and prolamine release in comparative pharmacological assays.